It could be you're finally developing a sensitivity to catheters. From what I've found, it eventually happens to most people who use catheters extensively and for a long time. As it did for me.
That sensitivity most certainly causes both pain and irritation (which may in turn be causing the mucus/blockages). IF this is the case, you might be able to get away changing to a different type of catheter (ie, 100% silicone vs latex, change the catheter size, use malecot vs balloon, etc as as few examples). Ultimately though, the only real solution to catheter sensitivity is to stop using them.
For now, I'd say try a different catheter and wait to see if it gets any better. But, also plan for the worse starting right now. Start looking into more permanent solutions (most likely surgery) that don't require catheters. IF it does get worse later on, then you won't be left scrambling for a pain free alternative.
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